Pesquisa | BVS IEC

1.

Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention.

Stephenson, Kathryn E; Wagh, Kshitij; Korber, Bette; Barouch, Dan H.

Annu Rev Immunol ; 38: 673-703, 2020 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-32340576

2.

Cocktail party: Low-dose antibody combinations deliver pan-ebolavirus protection.

Anthony, Scott M; Hensley, Lisa E.

Cell ; 185(6): 943-945, 2022 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-35303426

3.

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic.

Hoffmann, Markus; Krüger, Nadine; Schulz, Sebastian; Cossmann, Anne; Rocha, Cheila; Kempf, Amy; Nehlmeier, Inga; Graichen, Luise; Moldenhauer, Anna-Sophie; Winkler, Martin S; Lier, Martin; Dopfer-Jablonka, Alexandra; Jäck, Hans-Martin; Behrens, Georg M N; Pöhlmann, Stefan.

Cell ; 185(3): 447-456.e11, 2022 02 03.

Artigo em Inglês | MEDLINE | ID: mdl-35026151

4.

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.

Borriello, Francesco; Poli, Valentina; Shrock, Ellen; Spreafico, Roberto; Liu, Xin; Pishesha, Novalia; Carpenet, Claire; Chou, Janet; Di Gioia, Marco; McGrath, Marisa E; Dillen, Carly A; Barrett, Nora A; Lacanfora, Lucrezia; Franco, Marcella E; Marongiu, Laura; Iwakura, Yoichiro; Pucci, Ferdinando; Kruppa, Michael D; Ma, Zuchao; Lowman, Douglas W; Ensley, Harry E; Nanishi, Etsuro; Saito, Yoshine; O'Meara, Timothy R; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Dowling, David J; Frieman, Matthew; Elledge, Stephen J; Levy, Ofer; Irvine, Darrell J; Ploegh, Hidde L; Williams, David L; Zanoni, Ivan.

Cell ; 185(4): 614-629.e21, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-35148840

5.

SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape.

Li, Qianqian; Nie, Jianhui; Wu, Jiajing; Zhang, Li; Ding, Ruxia; Wang, Haixin; Zhang, Yue; Li, Tao; Liu, Shuo; Zhang, Mengyi; Zhao, Chenyan; Liu, Huan; Nie, Lingling; Qin, Haiyang; Wang, Meng; Lu, Qiong; Li, Xiaoyu; Liu, Junkai; Liang, Haoyu; Shi, Yi; Shen, Yuelei; Xie, Liangzhi; Zhang, Linqi; Qu, Xiaowang; Xu, Wenbo; Huang, Weijin; Wang, Youchun.

Cell ; 184(9): 2362-2371.e9, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33735608

6.

The antigenic anatomy of SARS-CoV-2 receptor binding domain.

Dejnirattisai, Wanwisa; Zhou, Daming; Ginn, Helen M; Duyvesteyn, Helen M E; Supasa, Piyada; Case, James Brett; Zhao, Yuguang; Walter, Thomas S; Mentzer, Alexander J; Liu, Chang; Wang, Beibei; Paesen, Guido C; Slon-Campos, Jose; López-Camacho, César; Kafai, Natasha M; Bailey, Adam L; Chen, Rita E; Ying, Baoling; Thompson, Craig; Bolton, Jai; Fyfe, Alex; Gupta, Sunetra; Tan, Tiong Kit; Gilbert-Jaramillo, Javier; James, William; Knight, Michael; Carroll, Miles W; Skelly, Donal; Dold, Christina; Peng, Yanchun; Levin, Robert; Dong, Tao; Pollard, Andrew J; Knight, Julian C; Klenerman, Paul; Temperton, Nigel; Hall, David R; Williams, Mark A; Paterson, Neil G; Bertram, Felicity K R; Siebert, C Alistair; Clare, Daniel K; Howe, Andrew; Radecke, Julika; Song, Yun; Townsend, Alain R; Huang, Kuan-Ying A; Fry, Elizabeth E; Mongkolsapaya, Juthathip; Diamond, Michael S.

Cell ; 184(8): 2183-2200.e22, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33756110

7.

SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2.

Amanat, Fatima; Thapa, Mahima; Lei, Tinting; Ahmed, Shaza M Sayed; Adelsberg, Daniel C; Carreño, Juan Manuel; Strohmeier, Shirin; Schmitz, Aaron J; Zafar, Sarah; Zhou, Julian Q; Rijnink, Willemijn; Alshammary, Hala; Borcherding, Nicholas; Reiche, Ana Gonzalez; Srivastava, Komal; Sordillo, Emilia Mia; van Bakel, Harm; Turner, Jackson S; Bajic, Goran; Simon, Viviana; Ellebedy, Ali H; Krammer, Florian.

Cell ; 184(15): 3936-3948.e10, 2021 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-34192529

8.

Pan-ebolavirus protective therapy by two multifunctional human antibodies.

Gilchuk, Pavlo; Murin, Charles D; Cross, Robert W; Ilinykh, Philipp A; Huang, Kai; Kuzmina, Natalia; Borisevich, Viktoriya; Agans, Krystle N; Geisbert, Joan B; Zost, Seth J; Nargi, Rachel S; Sutton, Rachel E; Suryadevara, Naveenchandra; Bombardi, Robin G; Carnahan, Robert H; Bukreyev, Alexander; Geisbert, Thomas W; Ward, Andrew B; Crowe, James E.

Cell ; 184(22): 5593-5607.e18, 2021 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-34715022

9.

Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress.

Williamson, Lauren E; Reeder, Kristen M; Bailey, Kevin; Tran, Minh H; Roy, Vicky; Fouch, Mallorie E; Kose, Nurgun; Trivette, Andrew; Nargi, Rachel S; Winkler, Emma S; Kim, Arthur S; Gainza, Christopher; Rodriguez, Jessica; Armstrong, Erica; Sutton, Rachel E; Reidy, Joseph; Carnahan, Robert H; McDonald, W Hayes; Schoeder, Clara T; Klimstra, William B; Davidson, Edgar; Doranz, Benjamin J; Alter, Galit; Meiler, Jens; Schey, Kevin L; Julander, Justin G; Diamond, Michael S; Crowe, James E.

Cell ; 184(17): 4430-4446.e22, 2021 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-34416147

10.

Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever.

Fels, J Maximilian; Maurer, Daniel P; Herbert, Andrew S; Wirchnianski, Ariel S; Vergnolle, Olivia; Cross, Robert W; Abelson, Dafna M; Moyer, Crystal L; Mishra, Akaash K; Aguilan, Jennifer T; Kuehne, Ana I; Pauli, Noel T; Bakken, Russell R; Nyakatura, Elisabeth K; Hellert, Jan; Quevedo, Gregory; Lobel, Leslie; Balinandi, Stephen; Lutwama, Julius J; Zeitlin, Larry; Geisbert, Thomas W; Rey, Felix A; Sidoli, Simone; McLellan, Jason S; Lai, Jonathan R; Bornholdt, Zachary A; Dye, John M; Walker, Laura M; Chandran, Kartik.

Cell ; 184(13): 3486-3501.e21, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-34077751

11.

Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques.

He, Xuan; Chandrashekar, Abishek; Zahn, Roland; Wegmann, Frank; Yu, Jingyou; Mercado, Noe B; McMahan, Katherine; Martinot, Amanda J; Piedra-Mora, Cesar; Beecy, Sidney; Ducat, Sarah; Chamanza, Ronnie; Huber, Sietske Rosendahl; van Heerden, Marjolein; van der Fits, Leslie; Borducchi, Erica N; Lifton, Michelle; Liu, Jinyan; Nampanya, Felix; Patel, Shivani; Peter, Lauren; Tostanoski, Lisa H; Pessaint, Laurent; Van Ry, Alex; Finneyfrock, Brad; Velasco, Jason; Teow, Elyse; Brown, Renita; Cook, Anthony; Andersen, Hanne; Lewis, Mark G; Schuitemaker, Hanneke; Barouch, Dan H.

Cell ; 184(13): 3467-3473.e11, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-34133941

12.

An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.

Liu, Yafei; Soh, Wai Tuck; Kishikawa, Jun-Ichi; Hirose, Mika; Nakayama, Emi E; Li, Songling; Sasai, Miwa; Suzuki, Tatsuya; Tada, Asa; Arakawa, Akemi; Matsuoka, Sumiko; Akamatsu, Kanako; Matsuda, Makoto; Ono, Chikako; Torii, Shiho; Kishida, Kazuki; Jin, Hui; Nakai, Wataru; Arase, Noriko; Nakagawa, Atsushi; Matsumoto, Maki; Nakazaki, Yukoh; Shindo, Yasuhiro; Kohyama, Masako; Tomii, Keisuke; Ohmura, Koichiro; Ohshima, Shiro; Okamoto, Toru; Yamamoto, Masahiro; Nakagami, Hironori; Matsuura, Yoshiharu; Nakagawa, Atsushi; Kato, Takayuki; Okada, Masato; Standley, Daron M; Shioda, Tatsuo; Arase, Hisashi.

Cell ; 184(13): 3452-3466.e18, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-34139176

13.

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.

Deng, Xianding; Garcia-Knight, Miguel A; Khalid, Mir M; Servellita, Venice; Wang, Candace; Morris, Mary Kate; Sotomayor-González, Alicia; Glasner, Dustin R; Reyes, Kevin R; Gliwa, Amelia S; Reddy, Nikitha P; Sanchez San Martin, Claudia; Federman, Scot; Cheng, Jing; Balcerek, Joanna; Taylor, Jordan; Streithorst, Jessica A; Miller, Steve; Sreekumar, Bharath; Chen, Pei-Yi; Schulze-Gahmen, Ursula; Taha, Taha Y; Hayashi, Jennifer M; Simoneau, Camille R; Kumar, G Renuka; McMahon, Sarah; Lidsky, Peter V; Xiao, Yinghong; Hemarajata, Peera; Green, Nicole M; Espinosa, Alex; Kath, Chantha; Haw, Monica; Bell, John; Hacker, Jill K; Hanson, Carl; Wadford, Debra A; Anaya, Carlos; Ferguson, Donna; Frankino, Phillip A; Shivram, Haridha; Lareau, Liana F; Wyman, Stacia K; Ott, Melanie; Andino, Raul; Chiu, Charles Y.

Cell ; 184(13): 3426-3437.e8, 2021 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-33991487

14.

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera.

Supasa, Piyada; Zhou, Daming; Dejnirattisai, Wanwisa; Liu, Chang; Mentzer, Alexander J; Ginn, Helen M; Zhao, Yuguang; Duyvesteyn, Helen M E; Nutalai, Rungtiwa; Tuekprakhon, Aekkachai; Wang, Beibei; Paesen, Guido C; Slon-Campos, Jose; López-Camacho, César; Hallis, Bassam; Coombes, Naomi; Bewley, Kevin R; Charlton, Sue; Walter, Thomas S; Barnes, Eleanor; Dunachie, Susanna J; Skelly, Donal; Lumley, Sheila F; Baker, Natalie; Shaik, Imam; Humphries, Holly E; Godwin, Kerry; Gent, Nick; Sienkiewicz, Alex; Dold, Christina; Levin, Robert; Dong, Tao; Pollard, Andrew J; Knight, Julian C; Klenerman, Paul; Crook, Derrick; Lambe, Teresa; Clutterbuck, Elizabeth; Bibi, Sagida; Flaxman, Amy; Bittaye, Mustapha; Belij-Rammerstorfer, Sandra; Gilbert, Sarah; Hall, David R; Williams, Mark A; Paterson, Neil G; James, William; Carroll, Miles W; Fry, Elizabeth E; Mongkolsapaya, Juthathip.

Cell ; 184(8): 2201-2211.e7, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33743891

15.

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies.

Hoffmann, Markus; Arora, Prerna; Groß, Rüdiger; Seidel, Alina; Hörnich, Bojan F; Hahn, Alexander S; Krüger, Nadine; Graichen, Luise; Hofmann-Winkler, Heike; Kempf, Amy; Winkler, Martin S; Schulz, Sebastian; Jäck, Hans-Martin; Jahrsdörfer, Bernd; Schrezenmeier, Hubert; Müller, Martin; Kleger, Alexander; Münch, Jan; Pöhlmann, Stefan.

Cell ; 184(9): 2384-2393.e12, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33794143

16.

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.

Winkler, Emma S; Gilchuk, Pavlo; Yu, Jinsheng; Bailey, Adam L; Chen, Rita E; Chong, Zhenlu; Zost, Seth J; Jang, Hyesun; Huang, Ying; Allen, James D; Case, James Brett; Sutton, Rachel E; Carnahan, Robert H; Darling, Tamarand L; Boon, Adrianus C M; Mack, Matthias; Head, Richard D; Ross, Ted M; Crowe, James E; Diamond, Michael S.

Cell ; 184(7): 1804-1820.e16, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33691139

17.

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.

McCallum, Matthew; De Marco, Anna; Lempp, Florian A; Tortorici, M Alejandra; Pinto, Dora; Walls, Alexandra C; Beltramello, Martina; Chen, Alex; Liu, Zhuoming; Zatta, Fabrizia; Zepeda, Samantha; di Iulio, Julia; Bowen, John E; Montiel-Ruiz, Martin; Zhou, Jiayi; Rosen, Laura E; Bianchi, Siro; Guarino, Barbara; Fregni, Chiara Silacci; Abdelnabi, Rana; Foo, Shi-Yan Caroline; Rothlauf, Paul W; Bloyet, Louis-Marie; Benigni, Fabio; Cameroni, Elisabetta; Neyts, Johan; Riva, Agostino; Snell, Gyorgy; Telenti, Amalio; Whelan, Sean P J; Virgin, Herbert W; Corti, Davide; Pizzuto, Matteo Samuele; Veesler, David.

Cell ; 184(9): 2332-2347.e16, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33761326

18.

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Garcia-Beltran, Wilfredo F; Lam, Evan C; St Denis, Kerri; Nitido, Adam D; Garcia, Zeidy H; Hauser, Blake M; Feldman, Jared; Pavlovic, Maia N; Gregory, David J; Poznansky, Mark C; Sigal, Alex; Schmidt, Aaron G; Iafrate, A John; Naranbhai, Vivek; Balazs, Alejandro B.

Cell ; 184(9): 2372-2383.e9, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33743213

19.

Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.

Thomson, Emma C; Rosen, Laura E; Shepherd, James G; Spreafico, Roberto; da Silva Filipe, Ana; Wojcechowskyj, Jason A; Davis, Chris; Piccoli, Luca; Pascall, David J; Dillen, Josh; Lytras, Spyros; Czudnochowski, Nadine; Shah, Rajiv; Meury, Marcel; Jesudason, Natasha; De Marco, Anna; Li, Kathy; Bassi, Jessica; O'Toole, Aine; Pinto, Dora; Colquhoun, Rachel M; Culap, Katja; Jackson, Ben; Zatta, Fabrizia; Rambaut, Andrew; Jaconi, Stefano; Sreenu, Vattipally B; Nix, Jay; Zhang, Ivy; Jarrett, Ruth F; Glass, William G; Beltramello, Martina; Nomikou, Kyriaki; Pizzuto, Matteo; Tong, Lily; Cameroni, Elisabetta; Croll, Tristan I; Johnson, Natasha; Di Iulio, Julia; Wickenhagen, Arthur; Ceschi, Alessandro; Harbison, Aoife M; Mair, Daniel; Ferrari, Paolo; Smollett, Katherine; Sallusto, Federica; Carmichael, Stephen; Garzoni, Christian; Nichols, Jenna; Galli, Massimo.

Cell ; 184(5): 1171-1187.e20, 2021 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-33621484

20.

High-resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies.

Garrett, Meghan E; Galloway, Jared; Chu, Helen Y; Itell, Hannah L; Stoddard, Caitlin I; Wolf, Caitlin R; Logue, Jennifer K; McDonald, Dylan; Weight, Haidyn; Matsen, Frederick A; Overbaugh, Julie.

Cell ; 184(11): 2927-2938.e11, 2021 05 27.

Artigo em Inglês | MEDLINE | ID: mdl-34010620

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Instituto Evandro Chagas

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